Apixaban


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August 31, 2010

Apixaban, Xarelto Deliver Good Results In Studies

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Pfizer and Bristol Myers Squibb's blood thinner apixaban beat aspirin in a study that may open the door to a multi-billion dollar-a-year market to prevent [...]

October 26, 2010

Global Drug Sales Seen Nearing 36 890 Bn In 2011

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of clot preventer developed by Pfizer and Bristol-Myers called apixaban and Vertex Pharmaceuticals Inc's hepatitis C treatment telaprevir, Aitken said. [...]

October 26, 2010

Jeffries Analysts Upgrades Bristol Myers (NYSE: BMY)

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of Bristol-Myers (NYSE :BMY) from “Buy” to “hold” in a research note to investors on Tuesday, citing increased expectations for apixaban and ipilimumab. [...]

August 31, 2010

New Factor Xa Inhibitor Better Than Enoxaparin For VTE Prevention ...


4 Mar 2010 Copenhagen, Denmark - The investigational anticoagulant apixaban (Bristol-Myers Squibb/Pfizer) is more effective than the dose of enoxaparin [...]

August 31, 2010

Bristol-Myers Squibb And Pfizer Provide Update On Apixaban ...


PRINCETON, NJ & NEW YORK--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE: BMY) and Pfizer Inc (NYSE: PFE) provided an update on the apixaban clinical [...]

October 26, 2010

Phase 3 AVERROES Clinical Trial Of Apixaban For Atrial ...


11 Jun 2010 Bristol-Myers Squibb Company and Pfizer today announced that the companies have agreed to stop the Phase 3 AVERROES clinical trial of [...]

October 26, 2010

Experimental Blood Thinner Apixaban Is 50% Better Than Aspirin At ...


31 Aug 2010 Researchers have prematurely terminated a clinical trial of an experimental blood thinner because the drug proved to be much better than [...]

October 26, 2010

Apixaban, Dabigatran, Rivaroxaban Thrombosis Adviser


Find out more about apixaban, dabigatran, and rivaroxaban on a Web site dedicated to information about new anticoagulation targets and single coagulation [...]

October 26, 2010

Success Stops Drug Trial: Apixaban Prevents Stroke In Patients ...


31 Aug 2010 The data monitoring committee of the AVERROES study, seeing overwhelming evidence of the success of apixaban in the prevention of stroke in [...]

August 31, 2010

Apixaban More Effective Than Enoxaparin Against VTE


The oral factor Xa inhibitor apixaban has been found superior to enoxaparin in preventing venous thromboembolism after knee-replacement surgery, with similar rates of bleeding, in a randomized placebo-controlled phase III trial. [...]

October 26, 2010

Bristol-Myers Squibb Third Quarter Featured Solid Operating Performance, Robust Clinical Data And The Strategic ...

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Bristol-Myers Squibb Company today reported results for the third quarter of 2010. Highlights in the quarter included: the presentation of new data on investigational compounds in the diabetes and cardiovascular disease franchises at major medical meetings; the completion of important regulatory milestones in the oncology, diabetes and immunoscience franchises; the acquisition of ZymoGenetics [...]

August 31, 2010

ADVANCE-2 Study Results Demonstrate Investigational ...


Phase III Data Published in The Lancet also Demonstrate Comparable Rates of Bleeding with Apixaban Versus Enoxaparin Mar 4, 2010 - Apixaban, an oral anticoagula [...]

August 31, 2010

Read This Post - Minyanville

Send by Lisa LaMotta

?This was not a head-to-head trial comparing apixaban to warfarin,? write Sanford Bernstein analyst Tim Anderson in a note to clients on Tuesday. ?Rather, it was evaluating apixaban versus aspirin in patients at risk of stroke who were [...]

August 31, 2010

SunTrust Banks: Upgrades, Downgrades

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Bristol-Myers (BMY) upgraded at Jefferies to Buy from Hold on increased expectations for apixaban and ipilimumab, and a low risk of losing US exclusivity [...]

October 26, 2010

Boehringer Beats Bayer, J&J To Market With Pradaxa Bloodthinner

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Boehringer Ingelheim GmbH won U.S. approval to sell Pradaxa, beating drugmakers including Bayer AG and Johnson & Johnson to the market with the first rival to the half-century-old blood thinner warfarin. [...]

October 26, 2010

AVERROES Trial Terminated Early: Apixaban Associated With ...

Send by Liz Jones Hollis

AVERROES trial terminated early: apixaban associated with "important" relative risk reduction for stroke and systemic embolism in AF Date : 31 Aug 2010 The phase 3 AVERROES (Apixaban Versus Read more [...]

August 31, 2010

AVERROES: Apixaban ??????????? ??????? ??? ???????? ? ?????????? ...


??????????? AVERROES, ?????????? ????????????? ? ????????????? ?? apixaban (Pfizer/Bristol-Myers Squibb) ? ??????? ??? ???????? ? ?????????? ???????, ?? ?????????? ??????????, ???? ???? ????? ?????? ?? ????????? ??????? ???????? [...]

October 26, 2010

The Clot Wars New Rivals To Warfarin As Blood Clot Preventer


For investors who have been asking themselves whether medium-size pharmaceutical companies can survive in an industry that has had recent mega-mergers, the answer seems to be yes. At least for Bristol-Myers Squibb. The company’s experimental anticoagulant drug apixaban worked better than aspirin in [...]

August 31, 2010

Apixaban Versus Enoxaparin For Thromboprophylaxis After Knee ...

Send by Michael Rud Lassen, Gary E Ras

Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial. By - Dr Michael Rud Lassen MD, Gary E Raskob PhD, Alexander Gallus MD, Graham [...]

August 31, 2010

Trial Comparing Apixaban To Aspirin In AF Stopped For Efficacy ...

Send by Larry Husten

The phase 3 AVERROES trial comparing apixaban to aspirin in 5600 AF patients unable to take warfarin has been stopped early by the Data Monitoring Committee after a predefined interim analysis found a significant reduction in stroke and [...]

August 31, 2010

BioPharma Today: Coming In Wednesday's "The Pink Sheet" DAILY ...

Send by Wendy Diller

Bristol-Myers/Pfizer's anticoagulant apixaban bests aspirin in preventing stroke in certain patients - Pharma industry agreements with Swedish government result in voluntary price reductions - Reckitt Benckiser receives FDA approval for [...]

August 31, 2010

PharmaGossip: Pfizer - Apixaban: Clinical Trials, Ain't They ...


Pfizer and Bristol-Myers Squibb's apixaban has suffered a setback in trials against So Apixaban was not "better" then enoxaparin. This means it's as good [...]

August 31, 2010

Apixaban Or Enoxaparin As Thromboprophylaxis In Knee Replacement ...

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In ADVANCE-2 3057 patients undergoing elective total knee replacement were randomised to oral apixaban 2.5mg twice a day, started 12 to 24 hours after surgery, or 40mg enoxaparin daily, started 12 hours before surgery. [...]

August 31, 2010

Rival Anti-Coagulants To Release Data Next Week | BioSmash

Send by Jack Shu

Next week, two rival anti-clotting pills are set to release their data. Bristol-Meyer's apixaban and Bayer's Xarelto are in a race to replace warfarin, the. [...]

October 26, 2010

Apixaban Success Halts Stroke Prevention Trial


Cnews health The data monitoring committee of the AVERROES study, seeing overwhelming evidence of the success of apixaban in the prevention of stroke in patients with atrial fibrillation who are unsuitable for the conventional treatment [...]


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