9 Oct 2010 Biotechnology company Amgen Inc. (AMGN) Friday said its investigational drug AMG 386, combined with paclitaxel, showed antitumor activity in [...]

Phase II Study of AMG 386 and Sorafenib as First-Line Therapy for Patients with Advanced or Inoperable Hepatocellular Carcinoma - Abou-Alfa, Ghassan, [...]

AMG 386 Pharmacokinetic parameters [ Time Frame: 2 years ] [ Designated as Incidence of the occurence of AMG 386 Antibody formation [ Time Frame: 2 [...]

9 Oct 2010 PRNewswire/ -- Amgen (Nasdaq: AMGN) today announced AMG 386, combined with paclitaxel, demonstrated antitumor activity in a randomized Phase [...]

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Its distinctive driving dynamics are a basic requirement for its challenging Formula 1 assignment: the AMG 6.3-litre V8 engine has a power output of 386 kW/525 hp, providing acceleration from zero to 100 km/h in 4.4 seconds. [...]

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THOUSAND OAKS, Calif., June 6, 2010 /PRNewswire via COMTEX/ –Amgen (Nasdaq: AMGN) today announced that AMG 386, combined with paclitaxel, demonstrated antitumor activity in a randomized Phase 2 trial involving 161 patients with [...]

The AMG 6.3-litre V8 engine in the E 63 AMG develops an output of 386 kW (525 hp) and a torque of 630 newton metres, matching the outstanding figures for the SL 63 AMG. The high-performance roadster has also donated its AMG SPEEDSHIFT [...]

Updated AMG 386 Data Demonstrate Promising Antitumor Activity in Patients With Recurrent Ovarian Cancer /* Style Definitions */ span.prnews_span { font-size:8pt; font-family:"Arial"; color:black; } span.prnews_wider [...]

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THOUSAND OAKS, Calif., Oct. 9 /PRNewswire/ -- Amgen (Nasdaq: AMGN) today announced AMG 386, combined with paclitaxel, demonstrated antitumor activity in a randomized Phase 2 trial involving 161 patients with recurrent ovarian cancer. The updated results, now including data on overall survival, are being presented in a poster discussion at the 35th European Society for Medical Oncology (ESMO [...]

478 kW (650 hp) and 820 Nm. 2005 saw the debut of the AMG 6.3-litre V8 engine; depending on the model, the naturally aspirated, high-revving M156 developed up to 386 kW (525 hp) and 630 Nm. Exclusively reserved for the new SLS AMG, [...]

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Experimental Design: Three cohorts of patients (F, n = 6; C/P, n = 8; D, n = 12) received one full cycle of chemotherapy alone during the pretreatment phase, followed by administration of AMG 386 10 mg/kg iv weekly in combination with [...]

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Romeo Ferraris presenta la sua interpretazione della Mercedes C63 AMG, forte dell'esperienza maturata nelle competizioni del campionato V8 Superstars. Dalla base dei 457 Cv… [...]

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Five investigational agents have been selected for the first phase of I-SPY2: Abbot Laboratories' ABT-888, or veliparib, a PARP inhibitor; Amgen's AMG 655, or conatumumab, an APO/TRAIL inhibitor, and AMG 386, an angiogenesis inhibitor; [...]

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against zoledronic acid and data from the phase III Vecitbix study Spectrum, as well as updates on pipeline treatments such as AMG 386 and AMG 479. Amgen Highlights Key Clinical Data to be Presented at European Society for . [...]

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The results showed that AMG 386 combined with weekly paclitaxel was highly efficacious and tolerable, with a manageable safety profile. PFS, the primary endpoint, significantly increased from 4.6 months with placebo to 7.2 months in the [...]

AMG 386 is a man-made medication that is designed to stop the development of Response based on biomarker, anti-AMG 386 antibody formation and tumor response [...]

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The company hopes to understand how the inhibition exhibited by AMG 386 compares with the better known VEGF pathway, and is optimistic that AMG 386 will show broad applicability across many tumor types. Another drug expected to work on [...]

The experimental drug, AMG 386 now in mid-stage trials has big potential to better starve tumors of their blood supply when used with standard medicines. AMG 386 helps block blood vessel formation by binding so-called angiopoietins 1 [...]

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THOUSAND OAKS, Calif., Oct. 9 /PRNewswire/ — Amgen (Nasdaq: AMGN) today declared AMG 386, compounded with paclitaxel, demonstrated antitumor state in a irregular Phase 2 effort involving 161 patients with continual ovarian cancer. [...]

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"Little focus has been placed on AMGN's late-stage cancer compounds AMG-479 and AMG-386," which each offer revenue potential of over $500 million, [...]